• Medium format 1,452.0mm2
  • 40.0 megapixels
  • ISO 200 - 1000
  • APS-C 369.0mm2
  • 20.9 megapixels
  • ISO 100 - 51,200

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Differences

Pentax 645D advantages over Nikon D500

  • Larger sensor
    Medium format vs APS-C
    More sensor area. Bigger is (generally) better.
  • Bigger pixels
    ~ 6.06 vs 4.22 microns
    Better low-light and dynamic range (all else equal)
  • More viewfinder magnification
    0.78x vs 0.67x
    Get a bigger view of the scene through the eye-level viewfinder
  • More pixels
    40.0 vs 20.9 megapixels
    Higher resolution photos

Nikon D500 advantages over Pentax 645D

  • Lens selection
    Excellent vs Limited
    Better lens selection gives you more options
  • Shoot 4K video
    4K (UHD) vs No
    Make sure you have a fast computer
  • Touchscreen
    Touch vs No touch
    Interact with your camera just like your smartphone
  • Tiltable Screen
    Tiltable vs Fixed
    Tilt the screen for shooting flexbility
  • Fast startup
    ~0.30 vs 0.7 sec
    Faster startup lets you catch the moment
  • Built-in Wi-Fi
    Wi-Fi vs None
    Share your photos wirelessly
  • NFC
    Yes vs No
    Simplifies pairing your camera with supported phones
  • Built-in Bluetooth
    Yes vs No
    Always-on wireless connectivity
  • More dynamic range
    14.0 vs 12.6 evs
    Retain detail in highlight and shadows
  • Longer stills battery life
    More info 1240 vs 800 shots
    Capture more photos
  • Thinner
    81 mm vs 119 mm
    Thinner
  • External Mic Jack
    Jack vs No jack
    Improved sound fidelity when shooting video
  • More cross-type AF points
    99 vs 11
    Cross-type AF points improve autofocus performance
  • Higher max flash sync
    1/250 vs 1/125 sec
    Reduce the effect of ambient light in flash shots
  • Newer
    9 years vs 14 years old
    Newer cameras often support more advanced features
  • Shoots 24p video
    Yes vs No
    Gives your movies a big-screen feel
  • Lighter weight
    856g vs 1480g
    Lighter weight
  • Higher-res screen
    590k vs 307k pixels
    More detail on the screen lets you judge focus and composition
  • Shoots 1080p video
    Yes vs No
    You'll want this if you shoot video
  • Shoots 60p video
    Yes vs No
    A faster framerate can give you more editing options
  • More AF points
    153 vs 11
    More AF points improve autofocus
  • Headphone jack
    Yes vs No
    Monitor audio recording while you shoot video
  • Faster JPEG shooting
    10.2 fps vs 1.1 fps
    Faster JPEG shooting (burst mode)
  • Bigger JPEG buffer
    200 vs 19 shots
    Take more JPEG shots before waiting (burst mode)
  • Faster RAW shooting
    10.2 fps vs 1.1 fps
    Faster RAW shooting in burst mode
  • Bigger RAW buffer
    200 vs 16 shots
    Larger buffer for RAW shots (burst mode)
  • Faster shutter
    1/8000 vs 1/4000 sec
    Shoot wide open in bright light
  • Higher extended ISO
    1638400 vs 1600 ISO
    Higher extended ISO can give more low-light flexibility

Similarities

Common Strengths

  • Eye-level viewfinder
    Both provide
    You'll be able to frame photos even when the sun is out
  • Top deck display
    Both provide
    Check settings with a screen on top of the camera
  • HDMI out
    Both provide
    Use HDMI output to monitor or review video
  • Hot shoe
    Both provide
    Off-camera flashes open new possibilities
  • Dual card slots
    Both provide
    Gives you more storage flexibility
  • Bulb shutter
    Both provide
    Hold the shutter open manually for long exposures

Common Weaknesses

  • Focus peaking
    Neither provide
    Your camera will highlight what's in focus
  • Tilt-swivel screen
    Neither provide
    Tilt and swivel the screen for maximum shooting flexibility
  • In-Camera Image Stabilization
    Neither provide
    Reduces the effects of camera shake at slower shutter speeds
  • In-camera panoramas
    Neither provide
    Stitches multiple shots into a panoramic photo
  • Built-in GPS
    Neither provide
    Geotag your photos
  • On-sensor phase detect
    Neither provide
    Usually improves live view and video AF performance
  • Internal flash
    Neither provide
    Useful in a pinch for fill flash
  • Slow-motion videos
    Neither provide
    Shoot slow-motion videos

User reviews

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Your purchases support this site

Buy the Pentax 645D

Your purchases support this site

Buy the Nikon D500

Review Excerpt

  • Very high-resolution 40-megapixel sensor; Plentiful controls with great placement; Excellent optical viewfinder; Dual SDHC card slots; Infrared remote sensors front and back.

  • High price tag; Aliasing artifacts; Produces ~70MB RAW files.

  • Superb image quality; Great high ISO performance; Rugged, comfortable camera body; Sharp articulating touchscreen display; Excellent AF point frame coverage; Fast continuous shooting speeds; 4K UHD video; Built-in Wi-Fi, NFC and Bluetooth.

  • Somewhat large for an APS-C camera; Expensive for a DX camera; 4K UHD video doesn't offer full DX field-of-view; No built-in flash; Still uses contrast-detect for Live View AF; Dual slots use two different card types (XQD and SD).

The Competition

Compared to Leica S2

Pentax 645D
Leica S2
  • $3599
  • Medium format
  • Less expensive
  • More cross-type AF points
  • $22995
  • Medium format
  • Thinner
  • More viewfinder magnification
Nikon D500
Leica S2
  • $1598
  • APS-C
  • Lens selection
  • Shoot 4K video
  • $22995
  • Medium format
  • Larger sensor
  • Bigger pixels

Compared to Leica S (Typ 006)

Pentax 645D
Leica S (Typ 006)
  • $3599
  • Medium format
  • Less expensive
  • Higher effective ISO
  • $10535
  • Medium format
  • Thinner
  • More viewfinder magnification
Nikon D500
Leica S (Typ 006)
  • $1598
  • APS-C
  • Lens selection
  • Shoot 4K video
  • $10535
  • Medium format
  • Larger sensor
  • Bigger pixels

Compared to Pentax 645Z

Pentax 645D
Pentax 645Z
  • $3599
  • Medium format
  • Fast startup
  • Longer stills battery life
  • $4845
  • Medium format
  • Focus peaking
  • Tiltable Screen
Nikon D500
Pentax 645Z
  • $1598
  • APS-C
  • Lens selection
  • Less expensive
  • $4845
  • Medium format
  • Focus peaking
  • Larger sensor

Compared to Pentax K-3 II

Pentax 645D
Pentax K-3 II
  • $3599
  • Medium format
  • Larger sensor
  • Bigger pixels
  • $830
  • APS-C
  • Lens selection
  • Focus peaking
Nikon D500
Pentax K-3 II
  • $1598
  • APS-C
  • Shoot 4K video
  • Touchscreen
  • $830
  • APS-C
  • Less expensive
  • Focus peaking

Compared to Sony A68

Pentax 645D
Sony A68
  • $3599
  • Medium format
  • Larger sensor
  • Bigger pixels
  • $598
  • APS-C
  • Lens selection
  • Focus peaking
Nikon D500
Sony A68
  • $1598
  • APS-C
  • Lens selection
  • Shoot 4K video
  • $598
  • APS-C
  • Less expensive
  • Focus peaking
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